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8VC
Tech-and-life-sciences firm backing bio-IT platforms across genomics, diagnostics, cell therapy, and biomanufacturing, and co-building companies through its in-house studio.
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Pre-SeedSeries AGrowth- Focus Areas
AI Models for BioBioInfrastructurePlatform BioSynthetic Biology- Notable Investments
- Fund Information
San Francisco, CA8vc.com - +
a16z
a16z's dedicated bio and health practice, investing across AI-driven drug discovery, next-generation diagnostics, and the software re-engineering how care is delivered.
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Pre-SeedSeries AGrowth- Focus Areas
AI Models for BioDiagnosticsNeuroPlatform Bio- Notable Investments
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San Francisco, CA / New York, NYa16z.com - +
AGE1
Earliest-stage longevity biotech fund backing contrarian founders building therapeutics and tools to extend healthy lifespan and treat age-related disease.
Solo GPEmerging Manager- Stages
Pre-SeedSeed- Focus Areas
NeuroPlatform BioSynthetic Biology- Notable Investments
- Fund Information
San Francisco, CAage1.com Solo-GP fund behind the annual State of AI Report, backing AI-first companies including TechBio and AI-native life sciences where machine learning is the core of the product.
Solo GPEmerging Manager- Stages
Pre-SeedSeed- Focus Areas
AI Models for BioNeuroPlatform BioSynthetic Biology- Fund Information
London, UKairstreet.comSeed-stage fund led by leading AI researchers, backing AI-native companies including a growing set applying machine learning to drug discovery, diagnostics, and cell biology.
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Pre-SeedSeries AGrowth- Focus Areas
AI Models for Bio- Notable Investments
- Fund Information
San Francisco Bay Area, CA, USAaixventures.comBerlin-based solo-GP seed fund backing European founders building where software, biology, and healthcare converge.
Solo GPEmerging Manager- Stages
Pre-SeedSeed- Focus Areas
AI Models for BioBioInfrastructurePlatform BioSynthetic Biology- Notable Investments
- Fund Information
Berlin, Germanyaminocollective.comAmplify Partners' dedicated digital-biology fund, first-checking technical founders who build in code as much as the lab, across AI drug discovery, simulation, and lab tooling.
Emerging Manager- Stages
Pre-SeedSeries AGrowth- Focus Areas
AI Models for BioBioInfrastructureNeuroPlatform Bio- Notable Investments
- Fund Information
Menlo Park, CA; San Francisco, CA, USAamplifypartners.com/amplify-bioCompany-building biotech investor backing breakthrough science at inception, increasingly concentrated on AI-driven drug discovery and computational biology.
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Pre-SeedSeries AGrowth- Focus Areas
AI Models for BioDiagnosticsNeuroPlatform BioSynthetic Biology- Notable Investments
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Chicago, ILarchventure.comSan Francisco firm credited with coining the term TechBio, investing from seed through growth across AI-driven diagnostics, cell therapy, and platform biology.
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Pre-Seed*Series AGrowth- Focus Areas
AI Models for BioMedical DevicesPlatform BioSynthetic Biology- Notable Investments
- Fund Information
San Francisco, CAav.coInception and seed stage venture firm partnering with founders at the edge of computation and biology, backing the AI, drug discovery platforms, diagnostics, and hardware that modernize how medicines are discovered, developed, and brought to market.
Solo GPEmerging Manager- Stages
Pre-SeedSeed- Focus Areas
AI Models for BioBioInfrastructureDiagnosticsNeuroPlatform Bio- Notable Investments
- Fund Information
San Francisco, CAatria.vcCentury-old multistage firm with a deep healthcare and life-sciences practice, backing AI-enabled drug development, clinical software, and digital health from seed to growth.
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Pre-Seed*Series AGrowth- Focus Areas
AI Models for BioPlatform Bio- Notable Investments
- Fund Information
Boston, MAbvp.comGrowth-equity firm investing in life-sciences technology, backing the B2B software, tools, and services that modernize how the industry runs.
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Growth- Focus Areas
BioInfrastructureDiagnosticsPlatform Bio- Fund Information
New York, NYbiospring.comSeattle frontier-tech fund founded by ex-Gates Foundation investors, backing breakthrough science where computation and biology reshape health and industry.
Emerging Manager- Stages
Pre-SeedSeries AGrowth- Focus Areas
AI Models for BioBioInfrastructurePlatform BioSynthetic Biology- Notable Investments
- Fund Information
San Francisco, CAbison.vcPre-seed, solo-GP fund backing scientist-founders at the frontier of genomics, machine intelligence, and new chemistries, at the intersection of biology and computation.
Solo GP- Stages
Pre-Seed- Focus Areas
AI Models for BioPlatform BioSynthetic Biology- Notable Investments
- Fund Information
San Francisco, CAboomcap.coSeed-to-Series-A bioscience fund backing founders where biology, chemistry, and computation converge to scale solutions in human health and sustainability.
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Pre-SeedSeedSeries A- Focus Areas
AI Models for BioBioInfrastructureDiagnosticsMedical DevicesNeuroPlatform BioSynthetic Biology- Notable Investments
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San Francisco, CAbreakout.vcPre-seed "near frontier" fund first-checking deeply technical founders across TechBio, climate, aerospace, and next-generation computing.
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Pre-SeedSeed- Focus Areas
AI Models for BioBioInfrastructurePlatform Bio- Notable Investments
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San Francisco, CAcantos.vcOperator-led, solo-GP biotech fund first-checking unorthodox technical founders in genomics, diagnostics, and AI-in-biotech.
Solo GP- Stages
Pre-Seed- Focus Areas
DiagnosticsMedical DevicesPlatform BioSynthetic Biology- Notable Investments
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San Francisco, CAcivilizationventures.comThesis-driven, research-intensive firm making contrarian "n-of-1" seed bets across AI, robotics, biology, and crypto, with a dedicated biology and computational-biology practice.
Emerging Manager- Stages
Pre-SeedSeed- Focus Areas
AI Models for BioBioInfrastructureNeuroPlatform Bio- Notable Investments
- Fund Information
New York, NYcompound.vc- +
DCVC
Deep-tech firm investing where computation meets the physical world, with its DCVC Bio practice backing AI-enabled life-sciences platforms over single drug candidates.
Multistage firm investing where machine learning meets biology, backing computational drug discovery alongside the software and lab automation that modernize biopharma.
Emerging Manager- Stages
Pre-SeedSeries AGrowth- Focus Areas
AI Models for BioBioInfrastructurePlatform Bio- Notable Investments
- Fund Information
San Francisco, CA / New York, NYdimensioncap.comFidelity-affiliated firm investing across biotech, diagnostics, and health technology from company creation through growth, including AI-enabled software tools for bioscientists.
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Pre-Seed*Series AGrowth- Focus Areas
BioInfrastructureMedical DevicesNeuro- Notable Investments
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Boston, MA / San Francisco, CA / London, UKfprimecapital.comOperator-led deep-tech seed fund backing founders solving civilization-scale problems across synthetic biology, climate, and food, with a program to turn scientists into founders.
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Pre-SeedSeedSeries A- Focus Areas
AI Models for BioDiagnosticsSynthetic Biology- Notable Investments
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San Francisco, CAfiftyyears.comGlobal investment firm whose Health Assurance thesis backs computational drug discovery, bioengineering, and life-sciences software from company creation onward.
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Pre-Seed*Series AGrowth- Focus Areas
AI Models for BioBioInfrastructureNeuro- Notable Investments
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San Francisco, CAgeneralcatalyst.com- +
GV
Alphabet-backed multistage firm investing across life sciences and AI, backing founders who use machine learning to accelerate drug discovery, diagnostics, and care.
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Series AGrowth- Focus Areas
AI Models for BioBioInfrastructureDiagnosticsNeuro- Notable Investments
- Fund Information
San Francisco, CAgv.com Pre-seed and seed deep-tech fund (a Susa Ventures spinout) backing founders across bio, robotics, climate, and defense, including generative-AI protein design.
Solo GPEmerging Manager- Stages
Pre-SeedSeed- Focus Areas
Platform BioSynthetic Biology- Notable Investments
- Fund Information
San Francisco, CAhumbaventures.comGlobal, contrarian seed generalist backing "outlier" founders worldwide, with a deep biotech thread spanning AI-driven drug discovery, diagnostics, and genomic data platforms.
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Pre-SeedSeries A- Focus Areas
BioInfrastructurePlatform Bio- Notable Investments
- Fund Information
Boston, MA / London, UKhummingbird.vcGlobal software-focused venture and growth firm with a life-sciences practice spanning computational drug discovery, AI clinical trials, and pharma data platforms.
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Series AGrowth- Focus Areas
AI Models for BioBioInfrastructure- Notable Investments
- Fund Information
San Francisco, CA / New York, NYinsightpartners.comAustin-based frontier-science firm reprogramming chemistry and biology, backing computational drug discovery, gene therapy, synthetic biology, and AI-enabled diagnostics.
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Pre-SeedSeedSeries A- Focus Areas
BioInfrastructurePlatform BioSynthetic Biology- Notable Investments
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Austin, TXkdtvc.comFirm known for bold, early bets on science experiments and frontier technology, including AI-driven drug discovery, genomics, diagnostics, and lab automation.
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Pre-SeedSeries AGrowth- Focus Areas
AI Models for BioBioInfrastructureDiagnosticsNeuroPlatform BioSynthetic Biology- Notable Investments
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San Francisco, CAkhoslaventures.comMultistage global generalist backing category-defining founders, with a healthcare-AI practice spanning clinical documentation, health data, and AI diagnostics.
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Pre-Seed*Series AGrowth- Focus Areas
DiagnosticsPlatform Bio- Notable Investments
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San Francisco, CA / Los Angeles, CAlsvp.comEli Lilly's corporate venture arm investing across biotech, health IT, and medtech from early to expansion stage, including AI-driven drug discovery, with access to Lilly's R&D ecosystem.
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Pre-SeedSeries AGrowth- Focus Areas
BioInfrastructurePlatform Bio- Notable Investments
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Indianapolis, IN, USA (global activity via hubs)lilly.com/science/partnersAI-augmented multistage biotech firm investing from seed through Series B in next-generation therapeutics, AI/ML drug discovery, and advanced diagnostics.
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Pre-SeedSeries AGrowth- Focus Areas
AI Models for BioDiagnosticsMedical DevicesNeuroPlatform Bio- Notable Investments
Character Biosciences, Curve Biosciences, Aeovian Pharmaceuticals
- Fund Information
New York, NY, USA (global presence)lumagroup.comScience-and-tech firm at the frontier of the physical and life sciences, with a Bio + Tech thesis spanning AI drug discovery and generative protein design.
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Pre-Seed*Series AGrowth- Focus Areas
AI Models for BioNeuroPlatform Bio- Notable Investments
- Fund Information
New York, NY / San Francisco, CAluxcapital.comEarly-stage firm investing at the intersection of deep tech and life sciences, backing AI/ML drug discovery, multi-omics, precision medicine, and tech-enabled clinical R&D.
Solo GPEmerging Manager- Stages
SeedSeries A- Focus Areas
AI Models for BioPlatform Bio- Notable Investments
- Fund Information
New York, NYmagneticvc.comFifty-year-old early-stage firm "all in on AI," investing at the bio-and-tech intersection across therapeutic platforms, AI drug discovery, life-science R&D software, and digital health.
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Series AGrowth- Focus Areas
AI Models for BioBioInfrastructurePlatform BioSynthetic Biology- Notable Investments
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San Francisco, CAmenlovc.com- +
NFX
Seed and pre-seed firm built around network effects, with a scientist-founder bio practice backing computational-biology bioplatforms and data-network-effect companies.
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Pre-SeedSeries A- Focus Areas
BioInfrastructurePlatform BioSynthetic Biology- Notable Investments
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San Francisco, CA / Israelnfx.com Venture and growth-equity firm backing founders driving structural change in healthcare and fintech, including AI-powered clinical insights, care navigation, and health infrastructure.
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Series AGrowth- Focus Areas
AI Models for BioBioInfrastructure- Notable Investments
- Fund Information
San Francisco, CAoakhcft.comFirm investing across planetary, human, and economic health, backing AI precision medicine, cryo-EM-plus-AI drug discovery, and generative biology.
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Pre-Seed*Series AGrowth- Focus Areas
AI Models for BioDiagnostics- Notable Investments
- Fund Information
San Francisco, CAobvious.comTechnology-first biotech firm investing at the convergence of biology and engineering, backing AI-enabled bio-tools, gene writing, synthetic biology, and molecular diagnostics.
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Pre-SeedSeries AGrowth- Focus Areas
BioInfrastructurePlatform BioSynthetic Biology- Notable Investments
- Fund Information
Chicago, ILomx.vcPre-seed and seed specialist with a dedicated biotech practice, backing platforms where automation and ML turn biology into an engineering discipline.
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Pre-SeedSeedSeries A- Focus Areas
DiagnosticsNeuroPlatform Bio- Notable Investments
- Fund Information
San Francisco, CApear.vcBoston seed firm whose Petri accelerator first-checks university spinouts pairing machine learning with the wet lab across protein design and synthetic biology.
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Pre-SeedSeed- Focus Areas
BioInfrastructurePlatform BioSynthetic Biology- Notable Investments
- Fund Information
Boston, MApetri.bioSolo-GP hard-tech seed fund first-checking founders commercializing real science, with a bio practice across drug discovery, genomics, and engineered biology.
Solo GP- Stages
Pre-SeedSeed- Focus Areas
AI Models for BioBioInfrastructurePlatform BioSynthetic Biology- Notable Investments
- Fund Information
Burlingame, CArefactor.comDeep-tech biotech fund run by the scientist-founders behind Mammoth Biosciences and Conception, backing early-career PhDs through a fellowship that takes no IP.
Emerging Manager- Stages
Pre-SeedSeed- Focus Areas
AI Models for BioPlatform BioSynthetic Biology- Notable Investments
portfolio is early-stage and largely undisclosed; names below mix the partners' lineage with selected disclosed companies
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San Francisco, CAscifounders.comCategory-defining multistage firm whose healthcare practice backs the application layer of medicine, from AI-native pharma to clinical-decision tools.
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Pre-SeedSeries AGrowth- Focus Areas
AI Models for BioMedical Devices- Notable Investments
- Fund Information
Menlo Park, CA; San Francisco, CA; London, UK (plus global affiliates)sequoiacap.comData-driven multistage firm running its own Beacon AI engine, first-checking applied-AI founders across clinical-data infrastructure and RNA foundation models.
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Pre-SeedSeedSeries AGrowth- Focus Areas
AI Models for BioBioInfrastructurePlatform Bio- Notable Investments
- Fund Information
San Francisco, CAsignalfire.comMultistage firm backing category-defining companies, with a life-sciences thread anchored by conviction bets on AI drug design and autonomous discovery.
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Series AGrowth- Focus Areas
AI Models for BioNeuro- Notable Investments
- Fund Information
New York, NY, USAthrivecap.comDeep-tech and health-tech firm backing applied AI as the enabling layer for century-defining life-science problems, from computational drug discovery to AI-driven scientific discovery.
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Pre-Seed*Series AGrowth- Focus Areas
BioInfrastructurePlatform BioSynthetic Biology- Notable Investments
- Fund Information
San Francisco, CAtriatomic.aiFounder-first seed firm with a deep health-and-biology practice, backing AI-driven drug development, microbiome science, and engineered biology at inception.
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Pre-SeedSeedSeries A- Focus Areas
BioInfrastructurePlatform BioSynthetic Biology- Notable Investments
- Fund Information
San Francisco, CAtrueventures.comLA pre-seed and seed fund backing biological platforms and applied robotics, from AI drug discovery and organoid screening to synthetic biology.
Solo GPEmerging Manager- Stages
Pre-SeedSeed- Focus Areas
AI Models for BioBioInfrastructureDiagnosticsMedical DevicesPlatform BioSynthetic Biology- Notable Investments
- Fund Information
Los Angeles, CAundeterredcapital.comAI-native seed firm backing intelligent B2B software that learns from data, with a bio thread spanning AI clinical-trial design and pharma data science.
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Pre-SeedSeedSeries A- Focus Areas
AI Models for BioBioInfrastructure- Notable Investments
- Fund Information
San Francisco, CA / New York, NYzettavp.com